Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
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چکیده
منابع مشابه
Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome.
Fragile X Syndrome (FXS) is the most common inherited form of intellectual disability, with behaviors characteristic of autism. Symptoms include abnormal social behavior, repetitive behavior, communication disorders, and seizures. Many symptoms of FXS have been replicated in the Fmr1 knockout (KO) mice. Whether Fmr1 KO mice exhibit vocal communication deficits is not known. By recording ultraso...
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ژورنال
عنوان ژورنال: Genes, Brain and Behavior
سال: 2012
ISSN: 1601-1848
DOI: 10.1111/j.1601-183x.2012.00781.x